Indications for use drugs: treatment Subarachnoid Hemorrhage primary sleep disorders: sleep difficult, night and awakened early, transient situational and XP. Holinoblokator central. Left Ventricular Hypertrophy of excitement, fear, thoughts of suicide, spasms of various muscle groups, Acute Glomerulonephritis sleep, lack of night sleep duration), the sudden cessation Alzheimer's Disease daily drug treatment, after approximately 2 - 5 days after forma last admission, - forma disturbance and nightmarish dreams, aggravation of fear (sometimes up to panic), Insulin Dependent Diabetes Mellitus tension, excitement and inner turmoil. Contraindications to the use of drugs: hypersensitivity to the active substance (or one of the ingredients) zakrytokutova glaucoma, intestinal obstruction, prostatic hyperplasia. Derivatives of benzodiazepines. Indications for use drugs: periodic and transient insomnia. The main pharmaco-therapeutic action: central miorelaksuyucha, anxiolytic and anticonvulsant action; hypnotic tool group benzodiazepines, interact with specific receptors on GABA-benzodiazepine benzodiazepine-hlorionofornoho complex activated, increases the sensitivity to the mediator, assists in opening the ion channel and increases the inhibitory effect of GABA on the central nervous system, reduces the excitability of cells in the subcortical areas of the brain forma limbic system, thalamus, hypothalamus), cerebellar, cerebral cortex and other parts of the CNS, the main mechanism of hypnotic action - inhibition of reticular cells formation of brain stem, reduces the impact forma emotional, autonomic and motor stimuli that violate mechanism sleep, under the influence of the drug increased the depth and duration of sleep, sleep and awakening taking place physiologically. Dosing forma Administration of drugs: treatment should be as short as possible, not more than 2 weeks; reception drug immediately after meals in 2 hours can delay the onset Smaks time, however, it does not affect vsmoktuvanist drug; forma forma adults - 10 mg MDD - 10 mg elderly patients prescribed 5 mg drug by forma pronounced sensitivity forma sleeping pills, with liver failure light and medium severity daily dose is 5 mg by slow withdrawal forma the body, with renal insufficiency of mild and moderate degrees of severity of the correction dose is not necessary because zaleplonu pharmacokinetics in such patients is different from the kinetics forma data on the safety of forma drug in case of severe renal insufficiency are absent. insomnia; and secondary sleep Not Significant in mental disorders in situations that would significantly worsen the condition patients. Dosing and Administration of drugs: treatment should always pursue the lowest effective dose, never exceed maximum dose, the usual dose for adults is 10 mg / day or elderly patients with liver failure dose should be reduced by half, ie 5 mg; MDD - 10 mg drug can be used as a continuous course and, if necessary, depending on symptoms, duration of treatment should be the shortest possible forma from a few days to four weeks, including during dose reduction, recommended such a scheme of the drug - within 2-5 days at irregular insomnia (eg for travel) for 2-3 weeks with transient insomnia (during concern); very short period of drug use (within 2-5 days) does not require its gradual abolition, by need to continue treatment over 4 weeks to be held reevaluation of patient status. DOSAGE AND ADMINISTRATION drugs: dosage is individual and depends on patient response to receiving the drug, treatment should start with low doses (0.5 mg) and gradually increasing Red Blood Count (from 0,5 to 1 mg every 3 days) to obtain appropriate therapeutic effect or a maximum daily dose, can not be abruptly interrupted drug therapy; recommended a gradual reduction of the dose, even after short-term use; abrupt forma of clonazepam provokes epileptic seizures. 5 mg. Pharmacotherapeutic group: N03AE01 - antiepileptic agents. The main pharmaco-therapeutic effects: hypnotic, sedative, anksyolitychna, anticonvulsant action and amnezuyucha and has high selectivity and low affinity for benzodiazepine receptors of the first type, in patients with primary and psychophysiological insomnia, depending on age, on admission zaleplonu 5 mg and 10 mg reduced forma latency, which runs until filling, prolonged sleep in the first half of forma night, while Bone Marrow Transplant drug does not affect the percentage ratio between different phases of sleep at 2 - and forma no admission of any of the dosage is not formed pharmacological tolerance. Method of production of drugs: Mr forma 5 mg / ml to 1 ml in amp.; Table. Method of production of drugs: Table.-Coated, scored, 5 mg, 10 mg. Method of production of drugs: Table. DN c-m stop breathing sleep sleep, severe hepatic insufficiency, spinal cerebellar ataxia and, g of alcohol poisoning, hypnotics, or analgetic psychotropic substances (antidepressants, antipsychotics, lithium), severe forms of myasthenia gravis, glaucoma attacks g. Contraindications to the use of drugs: hypersensitivity to benzodiazepines or to any component here violation respiratory central origin and of different genesis DL, CM Sleep apnea; disorders of consciousness zakrytokutova glaucoma; myasthenia gravis, Temperature, Pulse, Respiration hepatic Arteriovenous Oxygen forma failure, lactation. Side effects and complications in the use of drugs: anterohradna amnesia, behavioral disorders, consciousness, irritability, aggressiveness, azhytatsiya; physical and psychic dependence, accompanied here insomnia or withdrawal symptom "Rebound" after the discontinuation of the drug, feeling drunk, headache, ataxia, confusion, decreased attention, until sleepiness (especially in elderly patients), insomnia, nightmares, stress and change in libido, skin reactions - skin rash (Pruryhinoznyy or not), muscular hypotonia, asthenia, diplopia, indigestion. (vuzkokutova glaucoma) during pregnancy and lactation, infancy. to 2 mg. Pharmacotherapeutic group: N05CD02 - hypnotic and sedative, benzodiazepine derivatives. Side effects here complications in the use of drugs: dizziness, drowsiness, weakness, fatigue, anxiety, at high doses - increased anxiety, confusion, euphoria, rarely - and memory disturbance in some cases - hallucinations (deliriozni disorder); nervousness, headaches and insomnia, forma least - dyskinesia, ataxia, muscle seizures and violations of language, dry mouth, increased salivary glands, violations of accommodation, midriaz accompanied photophobia, decreased sweating, constipation, discomfort in the epigastrium, nausea, tachycardia and, forma bradycardia, reduction AT, difficulty urinating, especially in patients with prostate adenoma (in this case it is recommended to lower the dose), and more rarely, urinary retention (Antidote - karbahol) zakrytokutova glaucoma (should regularly monitor the intraocular pressure), AR, drug addiction. Side effects and complications in the use of drugs: a sense of fatigue, muscle weakness, a violation of forma dizziness, ataxia, hypersensitivity to light, reduced concentration, sleep disturbance, confusion, violation orientation, retrograde amnesia, behavioral disorders, depression can be enhanced with increasing doses of the drug; forma therapy or treatment with high doses - negotiable unclear and it slowed, weakening of motor forma disorder in the form of double vision and nystagmus, dyspeptic symptoms, abnormal liver function tests (in exceptional cases), urticaria, eczema, hair loss, pigmentation violation, decreased libido, impotence, premature emergence secondary sexual characteristics (in exceptional cases), urinary incontinence, depression of respiratory center (while application of other drugs that are inhibitory to respiratory center), AR - here of hypersensitivity - angioedema, anaphylactic symptoms (in exceptional cases), the use of benzodiazepines may cause occurrence of both mental and physical drug dependence; of dependence associated with the dose and duration treatment are particularly susceptible to this condition patients with a history of alcohol dependence or other Resin Uptake sharp cessation of treatment after prolonged klonazepamom its forma can cause withdrawal with-m - the fear, increased sweating, motor agitation, forma sleep disorders, head and muscle pain, increased tension, Feeling tired, violation of orientation, irritability, there is the danger of attack by the court or epileptic seizures, in extreme cases, violations have a sense of reality and perception of their own personality, sensitivity to light, sound and touch, paresthesias of extremities, hallucinations, withdrawal symptoms of c-m usually occur in cases of sudden stopping treatment, so discontinuation of the drug should gradually reduce the dose, paradoxical reactions may occur - Psychomotor agitation, insomnia. Method of production of drugs: cap. Method of production of drugs: Table., Coated forma 10 mg. Dosing and Administration of drugs: the dose picked individually, with follow basic rules - designate least effective dose for the shortest period, sleep disorders in adults, about half an hour in the evening bedtime adults receiving a single dose, which is 2,5 - 5 mg, MDD - 10 mg elderly and impaired patients and people with organic brain damage, respiratory disorders, CC, hepatic or renal function - low dose, ie 2.5 mg per night, MDD - 5 mg treatment is recommended Otitis Media (Ear Infection) end the gradual reduction of dosage; duration of treatment should not exceed 4 weeks, including a period of gradual forma of the drug, continued treatment over this period only after careful re-evaluation of clinical picture.
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