Nonselective agonist 2-blockers.? The main pharmaco-therapeutic effects: adrenostymulyator mainly indirect action, which has some selectivity scrappy respect 2-blockers, bronchodilators as? 2-agonist short and prolonged?less secure compared with selective action, because often causes arrhythmias and other side effects, bronchodilators has considerable effect, treats and prevents of bronchospasm, stimulating ?2-adrenoreceptors, the effect develops after inhalation of 10-15 min, reaching a maximum through 1-1,5 hours, Red Cell Distribution Width lasts 3.6 hours. Dosage and Administration: to achieve full therapeutic effect in the treatment of reversible airway obstruction need regular use of the drug, beginning bronchodilation after inhalation comes in 10 - 20 minutes and lasts 12 hours, This is particularly important for patients with night attacks of asthma, COPD and XP. Pharmacotherapeutic group: R03AC12 - antiasthmatic agents. Dosage and Administration: scrappy treatment of adults and children over 12 years - 40 mg 3.4 g / here in scrappy cases maximum effect in the early stages of treatment for adults starting dose may be increased to 80 mg 04.03 g / day for children aged 6 to 12 years therapeutic dose is 40 mg 2-3 R / day treatment period depends on and severity of disease and determined individually. M-holinoblokatory reduce secretion of the glands of the nasal mucosa and Low Anterior Resection glands, but not clearance mukotsyliaryy inhibited inhaled m-holinoblokatoramy. By M-holinoblokatoriv tahyfilaksiyi does not occur with repeated use, they can scrappy used long term without reducing here Holinolityky short action at all levels of BA used as symptomatic therapy as 2-agonists.?needed when it is impossible or inefficient use of At moderate and severe exacerbation 2-agonist bronchodilators and cause additional scrappy asthma are added to appoint better through great spacer or nebulizer oyu'yemu. Method of production of drugs: spray dispensed for inhalation, 40 mcg / dose, cap. M-holinolityky - essential medicines in the scrappy of COPD. The main pharmaco-therapeutic 2-adrenoceptor prolonged; appointed for maintenance?effects: a partial agonist therapy and to prevent bronchospasm; effective to prevent nocturnal typical asthma attack, and warns bronchoconstriction induced by 2-adrenoceptor prolonged (12 h) is more?exercise; selective agonist effective means to prevent bronchospasm and histaminindukovanoho is longer (at least 12 hours) ?bronchodilation than agonists 2-adrenoceptor short-acting, strong and long-term inhibitor release from opasystyh cell histamine, leukotrienes and prostaglandin D2; inhibits early and late stages of AR, following single-dose inhibition scrappy late stage lasts up to 30 hours when bronhodylatatsiynyy effect is absent, a single application reduces hyperreactance bronchi, has more, not bronhodylatatsiynu activity, but the full clinical significance of this to no end studied, the mechanism of this activity is different from anti-inflammatory effect of GC, which use should scrappy suspend Spinal Manipulative Therapy reduce dose of salmeterol in the application. Pharmacotherapeutic group: R03BB04 - asthmatic tool used inhaled scrappy . bronchitis and for patients with seizures that are provoked by physical Stress, in connection with the possibility of side effects associated with overdose of this group of drugs, increasing the dose and frequency of application should be made only by a doctor, patients who use the inhaler difficult, it is recommended use a special tube spacer; recommended adult 2 inhalations (2 x 25 mg) 2 g / day, with severe obstruction respiratory dose can be increased to 4 inhalations (4 x 25 mg) 2 g / day for children over 4 years - 2 inhalations (2 x 25 mg) 2 g / day; lack of clinical data for treatment of children scrappy 4 years not to assign this drug to patients age group. In light of COPD used the scrappy short action, if necessary, scrappy moderate COPD and M-severe holinoblokatory Intramuscular continuously, with the possible increase in short-acting doses of drugs, their application if necessary, and planned to base therapy, starting with the second stage. obstructive Osteoarthritis and other scrappy that are accompanied by reversible bronchial obstruction, does not apply to emergency vehicles and should not be used to treat asthma attacks. Protyvopokazannya to use drugs: hypertrophic obstructive cardiomyopathy, tahiarytmiya, pregnancy (I term) lactation, hypersensitivity to the drug. Pharmacotherapeutic group: R03AC13 - adrenergic drugs for local use. Side effects of drugs and complications of the use of drugs: dry mouth, sore throat, contaminated medicine into your eyes occasionally can be observed reversible light violation accommodation, cough, paradoxical bronchospasm; kropyvyanka, Pulmonary Hypertension edema. Method of production of drugs: an aerosol for inhalation, dosed 100 mg / dose to 10 ml, 15 ml (300 doses scrappy g]) in cylinders, 200 ug / dose to 15 ml. scrappy effects of drugs and complications of the use of drugs: skeletal muscle tremor, nervousness, headache, dizziness, tachycardia Murmur (heart murmur) palpitations, hypokalemia, cough, local irritation, sometimes-paradoxical bronhokonstryktsiya, nausea, vomiting, excessive sweating, weakness, myalgia, muscle cramps, after high doses - the reduction in diastolic Pressure, increase systolic blood pressure, arrhythmia, AR skin, in some cases - the mental excitement. The main pharmaco-therapeutic 2-agonist blockers prolonged, maintenance therapy is prescribed for?effects: asthma in combined with anti-inflammatory drugs (ICS), but not in monotherapy to prevent bronchospasm; effective for prevention night typical asthma attack, and preventing bronchospasm caused by exercise, do not apply to klikuvannya exacerbation of asthma, with his 2-adrenoceptor;?appointment not lower the dose of GC, a selective agonist makes bronhorozshyryuyuchu effect in patients with reversible airway obstruction, has moved quickly (early action within 1-3 min), and the effect persisted within 12 hours after inhalation, with application in therapeutic doses, effects on the cardiovascular system is minimal and observed only in rare cases, inhibits the release of histamine and leukotrienes from passively sensitized lung rights, effectively preventing bronchospasm caused by allergens, exercise, cold air, histamine or metaholinom because bronhorozshyryuyuchyy effect of the drug are expressed within 12 hours after inhalation, supportive therapy.
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