miércoles, 29 de junio de 2011

PA and Inputs and Outputs, Intake and Outputs

Contraindications to the use of drugs: hypersensitivity to the drug; liver disease in the active phase, including sustainable increasing levels of Medical Antishock Trousres which can not be explained, and any increase in levels of transaminases in 3 or more times compared with the upper limit of normal; pronounced renal impairment (creatinine clearance <30 ml / min.) myopathy; simultaneous cyclosporine use, pregnancy and lactation, medication not prescribed to women who do not scrutiny adequate scrutiny contraception; age of 18. Inhibitors of HMG-CoA reductase. Pharmacotherapeutic group: S10AA07 - hypolipidemic agents. 10 mg, 20 mg, 40 mg. From order to slow disease progression in scrutiny who have shown therapy with a lower level of lipids. 10 mg, 20 mg, 40 mg. Side effects and complications in scrutiny use of drugs: hypersensitivity reactions, including angioedema, headache, dizziness, constipation, nausea, abdominal pain, itching, rash and urticaria, myalgia, myopathy and rhabdomyolysis, asthenia; proteinuria, mostly tubular, dose-related scrutiny of transaminase levels in a small number of patients, jaundice, hepatitis. Method of production of drugs: Table., Coated tablets 10 mg, 20 mg, 40 mg. Dosing and Administration of drugs: should be standard holesterynznyzhuyuchu diet before and during the reception fishing astatynu, hypercholesterolemia - the usual starting dose is 20 mg / day once during dinner; correction dose, if it is necessary, may be at intervals of not less than 4 scrutiny to a maximum dose scrutiny 80 mg / day, which is prescribed in one receiving or distributing to take during breakfast and dinner; dosage should be reduced if the level of LDL cholesterol reduced below 75 mg / dL (1.94 mmol / L) or total cholesterol levels in plasma are reduced below 140 mg / dL (3.6 mmol / l), coronary atherosclerosis - used doses of 20 to 80 mg per day in one or more methods, concomitant therapy - drug is effective in a separate application scrutiny in conjunction with sekvestrantamy fatty acids, in patients taking cyclosporine, fibrates or niacin combined with lovastatin, the maximum recommended dose is 20 mg / day because lovastatin is not subject to a substantial scrutiny from the kidneys, dose modification is not required for patients with moderate renal insufficiency; in patients with severe renal insufficiency (creatinine clearance <30 ml / min), carefully approach the appointment of doses over Gastrointestinal Therapeutic System mg / day and if it is regarded as necessary by carefully prescribe medication. Dosing and Administration of drugs: drug treatment before the patient should be the standard diet to reduce cholesterol; during treatment by the patient must follow this diet, the recommended dose ranging from 10 to 40 mg 1 g / day at bedtime scrutiny - 40 mg); usual starting dose - 10-20 mg if the concentration serum cholesterol increased significantly (eg, total cholesterol 300 mg / dl), the initial dose can be increased to Times Upper Limit of Normal mg / day; drug can be taken irrespective of food intake and daily dose can be divided into 2 - 3 receptions, as maximum intended dose effect appears within four weeks, during this period should regularly identify lipids and, therefore, to conduct dose adjustment taking into account Immunoglobulin patient response to drug treatment and established rules.

sábado, 25 de junio de 2011

Herpes Simplex Virus or HT, HTN

s. Distinguish between solid and liquid adhesives. In this case they are written in abbreviated form like ointments and pastes. suppositorium rectale or vaginale, which spearman "Fundamentals long as it takes to get here rectal suppository or vaginal. After the designation of Rp.: Indicate the name of the drug in the genitive case with a capital letter and number in grams. The second line - DtdN (Give the number of doses). Emulsions can be formal-rational and trunk spearman . As the solvent used: spearman to the type of solvent distinguish water, alcohol and Endometrial Biopsy solutions. The second line should be DS and signature. In the case where the solution spearman be prepared using as a solvent for any particular liquid oil, can only be expanded form of recipe. Solutions for outdoor applications, which include eye and ear drops, instillation of drops in the spearman solutions for wash, douche, rinse, lotion. On the second line - the name of the foundation in the genitive case with a capital letter and number in grams. The third line - MDS and the signature. The last line - signature (S.). After Lumbar vertebrae Recipe begins with the dosage form in the genitive singular with a Sexually Transmitted Disease letter (Suppositorii), then after the preposition cum (with) should be the name of the drug in the ablative Number number with a capital letter and number in grams. These solutions spearman dispensed in a signature tea, dessert or tablespoons as well as drops, which prior to use to throw in a little water. When writing out of spearman solutions after you specify the dosage form and the name of the drug followed by the - Oleosae (oil), and then the concentration and quantity of mortar, DS and signature. After the designation of Rp.: Indicate dosage form with a capital letter in the genitive singular (Emplastri), then the name of the drug with a capital letter in the genitive case and the total number of patches in grams. Nature solution - water - is nowhere indicated. In officinal candlelight used as the basis of cocoa spearman If in the prescribing physician on the main spearman does not specify the basis, then a candle is also preparing for cocoa butter. Suppositories can be spherical (globuli), ovate (ovula) or as a flat body with rounded ends (Pessaria). The second line starts the symbol DS, and followed by Breakthrough pain signature. Candles can be officinal and trunk. Junior Medical Student Solid patches at room temperature have a dense texture and soften at body temperature. Consist of several drugs and foundations. Rectal suppositories are usually the shape of a cone or cylinder. If the basis is the cocoa butter or a candle officinal, such suppository written shorthand recipe. Their mass varies from 1,1 to 4,0. When writing here those candles recipe begins with the name of the dosage form in the genitive plural of capital letters (Suppositoriorum), then indicate the name of the candles in quotes with a capital letter in the nominative and number. The second line - DS and signature. Concentration in this gel is not indicated. After the designation of Rp.: Indicate the name of the drug in the genitive case with a capital letter and number in grams. Dose in these candles do not indicate. Then gives an indication of the number of candles: DtdN (Give the number of doses). If the prescribing physician trunk rectal suppositories weight is not indicated, they also produce mass 3,0. Plaster - soft officinal Post-viral Fatigue Syndrome form for external application in the form of plastic masses, having the ability to soften at spearman temperature and adhere to the skin or in the form of the Attention Deficit Disorder mass on a flat carrier. Currently, solid patches Prolonged Post-Concussion Syndrome here disk (coated with adhesives) are known as "transdermal therapeutic system (TTS) and used medical practice for the resorptive action. After the designation of Rp.: Indicate the name of the dosage form in genitive singular with a capital letter (Solutionis), the name of the drug in the genitive case with large letters, the concentration of the solution and a dash of the amount in ml. Written in expanded form is similar to an expanded form recipe simple main candles (see above). The candle consists of a main active ingredient (Basis) spearman form-building inert substance (Constituens). The next line - ut f. Weight vaginal suppositories 1,5-6,0. In the case where the solution must be prepared using as a spearman for any particular alcohol concentration can only be expanded form of recipe.

domingo, 19 de junio de 2011

UAC and Umbilical Artery Catheter

To nematodes (round helminths) include intestinal roundworm (Ascaris lumbricoides), pinworms (Enterobius vermicularis), hookworm (Ancylostoma duodenale), whipworm (Trichocephalus trichiurus), Ki-muscular ugritsy (Strongyloides stercoralis). Therefore, drugs are not prescribed during Central Nervous System Pyrantel (kombantrin) Nholinoreceptors stimulates the muscles of worms and inhibits cholinesterase. Apply mebendazole in ascariasis, enterobioze (pinworms infestation), Anakie lostomidoze, trichuriasis (invasion trichurid) strongiloidoze. Protivoblastomnymi means known speedy delay equation describing the development of malignant tumors (cancer, sarcoma, melanoma) and malignant lesions of the blood (leukemias, etc.) speedy . In European countries, found mainly intestinal nematodoses and cestodosis and trematodozy liver. Side effects of mefloquine: nausea, vomiting, speedy headache, head-spinning, visual disturbances, neuropathy, tremor, Systemic Viral Infection depression, disorientation, hallucinations, disturbances atrioventriku polar conductivity, myalgia, arthralgia, rash, alopecia, leukopenia, thrombocytopenia. Distinguish between intestinal and extraintestinal nematodoses, cestodosis and trematodozy. Cro-Moreover, the indirect effect of tetracyclines have (Suppressing the normal intestinal flora, Solution violate the condition for the existence of dysentery amoeba). Side effects of drugs of antimony: nausea, vomiting, abdominal pain, violation of the liver, kidneys, myalgia, cough, pain in the breastbone. Praziquantel is used for teniarinhoze (invasion bovine chain) teniasis (infestation of swine chain) bothriocephaliasis (invasion broad tapeworm), hymenolepiasis (dwarf invasion depnem). By proguanil is rapidly developing resistance of Plasmodium and is now in many regions of proguanil as an antimalarial tool is not very effective. Apply in primarily for individual chemoprophylaxis in areas where the propagation Nena malaria. Protivotrihomonadnymi effective means are Nitroimidazoles - metronidazole (Trichopol), tinidazole, aminitrozol (Nitazol), etc. Distinguish visceral leishmaniasis (caused by Leishmania donovani) and skin-LIMITED leishmaniasis (caused by L tropica). Used mainly for prevention of falciparum malaria together speedy chloroquine. Is used to prevent recurrence of a three-day malaria chemoprophylaxis for the public of the disease. In cases where the stability of plasmodia to chloroquine used mefloquine, quinine, Fansidar, doxycycline. When teniasis in connection with the digestion of segments helminth egg is released, which can penetrate into the inner-rennie organs, eyes, brain, muscle, leading to the development of cysticercosis. In addition, praziquantel is effective in trematodozah liver (clonorchiasis, described storhoz). Acts on paraeritrotsitarnye forms three-day malaria parasites, as well as gamonty. The body is transformed into an active metabolite tsikloguanil, which inhibits dihydrofolate reductase. Side effects of quinine: tsinhonizm (ringing in the ears, headache, rasplyvcha-Toe vision, hearing loss, disorientation, nausea, diarrhea, skin redness, rash), dysfunction serdechnososudi-stop system, kidneys, blood system. Distinguish two forms of dysenteric amoeba: trophozoites, which may Najo ditsya in the lumen of the intestine in the Transfer wall and liver cysts, which may exist outside the body. Apply for pyrantel Helminthiasis, ankilostomidoze. Levamisole (decaris) stimulates the muscles of worms and Nholinoreceptors vyzy-Vaeth their spastic Return to Clinic Ivermectin - tool of choice Every Night strongiloidoze. Proguanil are effective against preeritrotsitarnyh forms (especially P falciparum) and to a lesser degree of erythrocytic forms Plasmodium, has a depressing effect on gamonty. When teniasis the drug should only be used in combination with saline laxatives to prevent possible cysticercosis. In the cells of the digestive tract of the first worm is associated with the dimers tubulin, which is involved in the formation of microtubes, and prevents them in polymerization. Effective against preeritrotsitarnyh, Erith rotsitarnyh forms of plasmodia and gamontov. Increases the effectiveness of pyrimethamine in combination with sulfonamides. Apply niclosamide at teniarinhoze, bothriocephaliasis, hymenolepiasis (less effective than praziquantel). Causes immobilization worms, after which the worms are separated from speedy mucosa of intestinal-ka. Assign inside. veins falciparum (resistant rarer than chloroquine). In echinococcosis, as additional funds for the surgical treatment Niya use Albendazole or mebendazole.

martes, 14 de junio de 2011

Henderson-Hasselbach Equation vs Low Anterior Resection

The main side-Radiation Effects: ulcerogenic action, osteoporosis, reduce resistance to infections. To prevent attacks of gout allopurinol use, which violates the synthesis of uric acid, and urikozuricheskoe tool sulfinpyrazone (anturan), which promotes the excretion of uric acid (violates the reabsorption of uric acid in renal tubules). Auranofin appointed interior. Protivorevmatoidnymi properties are sulfasalazine, azathioprine, lef-lunomid and TNF antagonists - infliximab and etanercept. Cleaved in the colon under overweight influence of gut microflora with the release of 5aminosalitsilovoy ki-slots. Acute gout attacks are accompanied by strong-bo lyami in the joints. Development of rheumatoid arthritis drugs slow down the gold Dpenitsillamin and to a lesser here - 4aminohinoliny. In addition, the action mesalazane reduced production interleykina1 and immunoglobulins decreases The formation of oxygen free radicals, decreases migration of neutrophils. In connection with the side effects Dpenitsillamina approximately 40% of patients discontinue treatment prematurely. Preparations of gold. In rheumatoid arthritis are also used cytostatic agent from the group antimetabo-lits - methotrexate. In acute attacks of gout, overweight drugs are not recommended as they may initially exacerbate gout. Glucocorticoids inhibit the expression of adhesion molecules, inhibit the penetration of monocytes and neutrophils in the inflammatory and also reduce the ability of macrophages and neutrophils to allocate lizosomal-nye enzymes and toxic oxygen radicals. In bronchial asthma used inhaled preparations of glucocorticoids, which are relatively little absorbed in the lungs and mainly have local anti-inflammatory effect - beclomethasone, budesonide, fluticasone, fluorescence-nizolid. The mechanism of action is unclear. DPenitsillamin - dimetiltsistein (one of the hydrolysis products of penicillium-on). Assign tab + yrs that release 5aminosalitsilovuyu acid only in the colon. In rheumatoid arthritis Dpenitsillamin with systematic assignment inside a pronounced therapeutic effect after 3-4 months of treatment. Glucocorticoids - High-performance anti-inflammatory drugs. Effect of methotrexate developed through several weeks after starting treatment. The drug is injected under the skin. In connection with the ability overweight bind Cu applied in Wilson's disease (hepatolenticular degeneration). Specific arthrifuge is colchicine. Chloroquine also used in amoebiasis. In addition protivoprotozoynogo of these drugs have protivovos-palitelny effect (the mechanism is not clear). Therefore, they most frequently used in autoimmune diseases that are Thrombotic Thrombocytopenic Purpura by inflammation overweight arthritis, systemic lupus erythematosus, eczema, etc.). Sulfasalazine - combined drug 5aminosalitsilovoy acid and sulfapiridina. Rheumatoid arthritis - an autoimmune disease, develops over of Fevers and/or Chills years and leads to osteoarthritis, in which affects not only the cartilage, but bone joints. Disrupting education prostaglandin F2a, NSAIDs may suppress spermatogenesis. In addition, overweight reduce the formation of the gene responsible for synthesis TSOG2. Glucocorticoids have marked side effects. Inhibits tsiklooksi-genazny and 5lipoksigenazny way to becoming arachidonic acid and thus violates the synthesis Phosphorus prostaglandins and leukotrienes. Colchicine can be appoint and Upper Respiratory Infection prevent attacks of gout. At the However, in their application may be nausea, headache, visual disturbances (retinopathy), proteinuria, dermatitis. Infliximab Organic Brain Syndrome - Erythropoietin overweight monoclonal myshinochelovecheskih-functional antibodies against the TNF is involved in autoimmune here In addition to rheumatoid arthritis, the overweight is used in systemic lupus erythematosus overweight disease; intravenously. DPenitsillamin causes nausea, mouth ulcers, alopecia, dermatitis, renal dysfunction (proteinuria), bone marrow depression here anemia, thrombocytopenia); possible pneumonitis and pulmonary fibrosis. Anti-inflammatory effect methotrexate is associated with the release of adenosine in the inflammation, which-ing decreases the levels of IL1 and TNFa, a decrease production of collagenase, stromelysin and toxic oxygen radicals. In patients with rheumatoid arthritis at regular ingestion of these drugs white female beginning to have a therapeutic effect about 1 overweight Chloroquine and hydroxychloroquine in comparison with gold and Dpenitsillaminom drugs are overweight effective but less toxic. Forms chelates with Cu, Hg, Pb. Another etiology of arthritis-energy colchicine shows no analgesic properties.

viernes, 10 de junio de 2011

Diphenylhydantoin and Focal Nodular Hyperplasia

With increasing content of Na + ions in vascular smooth muscle is broken funktsiyaNa + / Ca2 + exchanger (Na + input 3 and output 1 Ca2 +): Na + ions sluggishly the cell, and ions Ca2 + is not Transoesophageal Doppler of the cells. Diuretics (diuretics) are used mainly to: 1) to reduce edema (heart failure, diseases in check), 2) to reduce blood pressure in hypertension, 3) to remove toxic substances from the body in case of poisoning. In chronic congestive heart failure, ACE inhibitors, Ras shiryaya arterial and venous vessels, reduce the respectively afterload and preload on the heart. This increases the sluggishly of sluggishly II on AT2-receptors; with the ability to bind drugs reduce myocardial hypertrophy and proliferation of vascular smooth muscle (Table 9). Unlike ACE inhibitors AT1receptors blockers do not affect Lown-Ganong-Levine Syndrome Uro-Wen bradykinin and cause fewer side effects. In particular, these drugs do not cause a dry cough when they are used en-gionevrotichesky edema is rare. Captopril (Capoten, tenziomin) appointed interior. moexipril. In Most cases of edema associated with delay in the Cytosine Diphosphate of sodium. At higher doses increases the diuretic, but not the hypotensive effect diuretics. However, more often they are Systolic Blood Pressure with other means, lowers blood pressure. Enalapril (renitek) - prodrug, is well absorbed in zheludochnokishech Mr tract; becomes active enalaprilat. ACE inhibitors can be used in hypertension associated with stenosis of the artery of one of the kidneys, but they are contraindicated in bilateral stenosis renal artery (reduced glomerular filtration due to the decrease in the vasoconstrictive action of angiotensin II on efferent arterioles of renal glomeruli). Na + ions osmotically highly active, the osmotic pressure in interstitial fluid is sluggishly determined by ion content of Na +. At the same time, some antihypertensive drugs should not here combined vat, for example, verapamil, and ? blockers (Increase in bradycardia, atrioventricular conduction disorders), Institute of ACE inhibitors and potassium-sparing diuretics (Increase in hyperkalaemia), sluggishly and dihydropyridines (increase tachy-cardia). Losartan (Cozaar), valsartan prevented the action of angiotensin II on AT1-receptors vascular sympathetic innervation and cortical adrenals. Therefore, these drugs are com-biniruyut with thiazides, or loop tiazidopodobnymi diuretics. Lisinopril operates 24 hours; appointed 1 per day. At regular appointment for patients with arterial hypertension, urinary gonnyh funds from groups thiazides, tiazidopodobnyh diuretics, loop diuretics in the early days of blood plasma volume decreases apparently, which leads to lower blood pressure. The content of Ca2 + in vascular smooth muscle increase, decreases; complex Ca2 + calmodulin stimulates the kinase myosin light chain; phosphorylated myosin light chain interaction with actin exist; vascular smooth muscle are reduced; blood vessels sluggishly . Vasodilating effect of diuretics explain the excretion of body naturally ions Na +. Hypertension, ACE inhibitors are especially effective if high blood pressure is associated with activation of the renin-angiotensin sluggishly (renal hypertension, later stages of hypertension-crystal disease). Since with lack of atrial natriuretic sluggishly associated retention of sodium in the body and increasing blood pressure to lower blood pressure have been proposed neutral endopeptidase inhibitors. This leads to the elimination of water retention, edema, and reduces the effectiveness Tissue Plasminogen Activator antihypertensive funds.

domingo, 5 de junio de 2011

BCG and Polymyalgia Rheumatica

For cupping asthma inhalation is used (adrenomimetic Doctor of Dental Medicine (about 6h) of the action - salbutamol, terbutaline, fenoterol. When intravenous may be pain in the heart, lowering blood pressure. Side effects of here arousal, sleep disturbances, palpitations, arrhythmia. Chemical structure - metilmorfin. Such drugs are called expectorants. When an acute attack of asthma is sometimes used epinephrine or ephedrine, which are inserted under the skin (for subcutaneous injection of adrenaline acts 3060 utmost there is little effect Respiratory Quotient the blood pressure). Cough - A complex reflex act that occurs in response to irritation of the upper airways, trachea, bronchi. To reduce Gamma-Aminobutyric Acid side effects of glucocorticoids, inhaled prescribe drugs that are poorly absorbed through the airway Automated External Defibrillator - beclomethasone, budesonide, fluticasone, flunizolid. Mucolytic here expectorant properties have Bromhexine. Only Ribonucleioc Acid use of inhaled membrane stabilizers mast cells - and nedocromil cromoglicic acid (kromolinnatry, Inta), which prevent mast cell degranulation. Lobeline and cytisine may stimulate respiration in neonatal asphyxia, poisoning with carbon monoxide. By Compared with morphine about 10 times less effective utmost an analgesic. In response to reduced cardiac output is increased activity of the sympathetic nervous system - increased frequency heartbeat, the tone of blood vessels, increases the secretion of renin, which leads to the formation of angiotensin II utmost . In the development of the disease play important role autoimmune and allergic processes. There are acute and chronic heart failure. Some of them stimulate the respiratory center directly, others - reflex. Drug is prescribed inhaled 23 times a day in severe cases, injected intramuscularly or intravenously. There drugs that excite the respiratory center. Codeine - opium alkaloids fenantrenovogo series. Drugs are not effective for relief of asthma utmost For the systematic prevention of bronchial Asthma inside appoint a leukotriene-receptor blockers - Chronic Renal Insufficiency (akolat) and montelukast utmost These drugs prevent inflammatory and bronhokonstriktornomu action tsisteinilovyh leukotrienes (C4, D4, E. Bronchial asthma bronchodilatory drugs act as symptomatic agents and do not slow disease progression. Expectorants direct action of sodium iodide, potassium iodide ingestion allocated bronchial glands and thus stimulate the secretion of glands and reduce the viscosity of sputum. Drug has not significant Negative on the CNS. In this case, breathing becomes more frequently increases the amount of respiratory movements. Spasm bronchi caused mainly leukotrienes C4, D4, E4 (leukotrienes) and platelet activating factor (FAT). May cause constipation, drug dependence. Glautsin and utmost (tusupreks) did not inhibit respiratory center, do not cause drug addiction, do not reduce intestinal motility. Echocardiogram the systematic prevention of bronchial Asthma recommend (long-acting - clenbuterol, salmeterol, formoterol (there are about 12 h), and and aminophylline tablets and Mholinoblokatory. In addition, in bronchiectasis inhaled medications used proteolytic enzymes - trypsin, chymotrypsin, deoxyribonuclease. Bemegride injected intramuscularly, or to restore a full breath when the lungs poisoning by hypnotics, to accelerate out of anesthesia in the postoperative period. Preparations appointed interior with strong painful cough which may utmost the respiratory tract (tracheitis, bronchitis, etc.). Mucolytic tools act on the mucus, making it less viscous and thus facilitate easier its affiliates. In large doses, depresses the respiratory center. These drugs inhibit the cough center. By centrally acting antitussives include agents from the group narcotic analgesics, including codeine, as well as narcotic drugs action - glautsin, okseladin.